New reaction facilitates drug discovery

Chemists at ETH Zurich have found a facile method that allows a commonly used building block to be directly converted into other types of important compounds. This expands the possibilities of chemical synthesis and facilitates the search for new pharmaceutically active ingredients.

Two chemical compounds, on the left: Indol
ETH Zurich chemists have succeeded in incorporating an additional nitrogen atom into an indole (left).  (Visualisations: Adobe Stock / Montage)
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